5IH4

Human Casein Kinase 1 isoform delta apo (kinase domain)

Summary for 5IH4

Entry DOI	10.2210/pdb5ih4/pdb
Descriptor	Casein kinase I isoform delta, ZINC ION, S,R MESO-TARTARIC ACID, ... (5 entities in total)
Functional Keywords	kinase domain, stem cell reprogramming, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P48730
Total number of polymer chains	1
Total formula weight	34614.15
Authors	Ursu, A.,Illich, D.J.,Takemoto, Y.,Porfetye, A.T.,Zhang, M.,Brockmeyer, A.,Janning, P.,Watanabe, N.,Osada, H.,Vetter, I.R.,Ziegler, S.,Schoeler, H.R.,Waldmann, H. (deposition date: 2016-02-29, release date: 2016-04-13, Last modification date: 2024-01-10)
Primary citation	Ursu, A.,Illich, D.J.,Takemoto, Y.,Porfetye, A.T.,Zhang, M.,Brockmeyer, A.,Janning, P.,Watanabe, N.,Osada, H.,Vetter, I.R.,Ziegler, S.,Scholer, H.R.,Waldmann, H. Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23:494-507, 2016 Cited by PubMed: 27049670 DOI: 10.1016/j.chembiol.2016.02.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation