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5IBN

Ultra high resolution crystal structure of the apo- form of second bromodomain of BRD2.

Summary for 5IBN
Entry DOI10.2210/pdb5ibn/pdb
DescriptorBromodomain-containing protein 2, CHLORIDE ION, GLYCEROL, ... (5 entities in total)
Functional Keywordsbet-family, acetyl-lysine binding, transcription
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : P25440
Total number of polymer chains1
Total formula weight13849.23
Authors
Tripathi, S.K.,Padmanabhan, B. (deposition date: 2016-02-22, release date: 2016-06-22, Last modification date: 2023-11-08)
Primary citationTripathi, S.,Mathur, S.,Deshmukh, P.,Manjula, R.,Padmanabhan, B.
A Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the Complex
Plos One, 11:e0156344-e0156344, 2016
Cited by
PubMed: 27243809
DOI: 10.1371/journal.pone.0156344
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (0.94 Å)
Structure validation

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