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5I7M

Crystal structure of Y345F mutant of human primase p58 iron-sulfur cluster domain

Summary for 5I7M
Entry DOI10.2210/pdb5i7m/pdb
DescriptorDNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION, ... (4 entities in total)
Functional Keywordsdna replication, primase, [4fe-4s], p58c, replication
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight44219.08
Authors
Salay, L.E.,Thompson, M.K.,Chazin, W.J. (deposition date: 2016-02-17, release date: 2017-03-01, Last modification date: 2023-09-27)
Primary citationO'Brien, E.,Holt, M.E.,Thompson, M.K.,Salay, L.E.,Ehlinger, A.C.,Chazin, W.J.,Barton, J.K.
The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355:-, 2017
Cited by
PubMed: 28232525
DOI: 10.1126/science.aag1789
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

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