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5I6U

The crystal structure of PI3Kdelta with compound 32

Summary for 5I6U
Entry DOI10.2210/pdb5i6u/pdb
Related5I4U
DescriptorPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, 2-[(1S)-1-({6-amino-5-[(1H-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3H)-one (2 entities in total)
Functional Keywordskinase, p110, kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceMus musculus (Mouse)
Cellular locationCytoplasm : O35904
Total number of polymer chains1
Total formula weight108249.53
Authors
Somoza, J.R.,Villasenor, A.G. (deposition date: 2016-02-16, release date: 2017-02-22, Last modification date: 2023-09-27)
Primary citationSomoza, J.R.,Villasenor, A.G.
The crystal structure of PI3Kdelta with compound 32
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.842 Å)
Structure validation

217705

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