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5I59

Glutamate- and glycine-bound GluN1/GluN2A agonist binding domains with MPX 007

Summary for 5I59
Entry DOI10.2210/pdb5i59/pdb
Related5I56 5I57 5I58
DescriptorGlutamate receptor ionotropic, NMDA 1,Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A,Glutamate receptor ionotropic, NMDA 2A, GLYCINE, ... (6 entities in total)
Functional Keywordsnmda receptor, antagonist, transport protein, receptor
Biological sourceRattus norvegicus (Rat)
More
Total number of polymer chains2
Total formula weight65550.78
Authors
Mou, T.-C.,Sprang, S.R.,Hansen, K.B. (deposition date: 2016-02-14, release date: 2016-09-21, Last modification date: 2023-09-27)
Primary citationYi, F.,Mou, T.C.,Dorsett, K.N.,Volkmann, R.A.,Menniti, F.S.,Sprang, S.R.,Hansen, K.B.
Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.
Neuron, 91:1316-1329, 2016
Cited by
PubMed: 27618671
DOI: 10.1016/j.neuron.2016.08.014
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

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