5I4R

Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified)

Summary for 5I4R

• Entry DOI: 10.2210/pdb5i4r/pdb
• Descriptor: Contact-dependent inhibitor A, Elongation factor Tu, Contact-dependent inhibitor I, ... (5 entities in total)
• Functional Keywords: toxin, antitoxin, elongation factor, structural genomics, psi-biology, midwest center for structural genomics, mcsg, structure-function analysis of polymorphic cdi toxin-immunity protein complexes, uc4cdi, toxin-antitoxin complex, toxin/antitoxin
• Biological source: Escherichia coli NC101; More
• Total number of polymer chains: 8
• Total formula weight: 133836.14

Authors

Michalska, K.,Stols, L.,Eschenfeldt, W.,Hayes, C.S.,Goulding, C.W.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) (deposition date: 2016-02-12, release date: 2017-06-28, Last modification date: 2023-11-15)

• Primary citation: Michalska, K.,Gucinski, G.C.,Garza-Sanchez, F.,Johnson, P.M.,Stols, L.M.,Eschenfeldt, W.H.,Babnigg, G.,Low, D.A.,Goulding, C.W.,Joachimiak, A.,Hayes, C.S.; Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.; Nucleic Acids Res., 45:10306-10320, 2017; PubMed: 28973472; DOI: 10.1093/nar/gkx700

Experimental method

X-RAY DIFFRACTION (3.3 Å)