5I3O
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
Summary for 5I3O
Entry DOI | 10.2210/pdb5i3o/pdb |
Related | 4W9W 4W9X 5I3R |
Descriptor | BMP-2-inducible protein kinase, N-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1H-indazol-3-yl)cyclopropanecarboxamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | transferase, protein kinase domain, structural genomics, structural genomics consortium, sgc, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 69019.42 |
Authors | Counago, R.M.,Sorrell, F.J.,Krojer, T.,Savitsky, P.,Elkins, J.M.,Axtman, A.,Drewry, D.,Wells, C.,Zhang, C.,Zuercher, W.,Willson, T.M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Arruda, P.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2016-02-10, release date: 2016-03-09, Last modification date: 2023-09-27) |
Primary citation | Counago, R.M.,Sorrell, F.J.,Krojer, T.,Elkins, J.M.,Gileadi, O.,Willson, T.M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Arruda, P. Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report