5I33

Unligated adenylosuccinate synthetase from Cryptococcus neoformans

Summary for 5I33

• Entry DOI: 10.2210/pdb5i33/pdb
• Related: 5I34
• Descriptor: Adenylosuccinate synthetase (2 entities in total)
• Functional Keywords: dimer, adenylosuccinate synthetase, purine metabolism, ligase
• Biological source: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)
• Cellular location: Cytoplasm : J9VI09
• Total number of polymer chains: 2
• Total formula weight: 95878.94

Authors

Blundell, R.D.,Williams, S.J.,Ericsson, D.,Fraser, J.A.,Kobe, B. (deposition date: 2016-02-09, release date: 2016-08-24, Last modification date: 2023-09-27)

• Primary citation: Blundell, R.D.,Williams, S.J.,Arras, S.D.,Chitty, J.L.,Blake, K.L.,Ericsson, D.J.,Tibrewal, N.,Rohr, J.,Koh, Y.Q.,Kappler, U.,Robertson, A.A.,Butler, M.S.,Cooper, M.A.,Kobe, B.,Fraser, J.A.; Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans.; Acs Infect Dis., 2:651-663, 2016; PubMed: 27759389; DOI: 10.1021/acsinfecdis.6b00121

Experimental method

X-RAY DIFFRACTION (2.2 Å)