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5I25

human recombinant coagulation FXI in complex with a peptide derived from human high molecular weight kininogen (HKP)

Summary for 5I25
Entry DOI10.2210/pdb5i25/pdb
Related5EOD 5EOK
DescriptorCoagulation factor XI, ASN-PRO-ILE-SER-ASP-PHE-PRO-ASP, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordscoagulation fxi, high molecular weight kininogen, hydrolase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight69684.17
Authors
Hall, G.A.F.,Wong, S.S.,Emsley, J. (deposition date: 2016-02-08, release date: 2016-04-06, Last modification date: 2020-07-29)
Primary citationWong, S.S.,stergaard, S.,Hall, G.,Li, C.,Williams, P.M.,Stennicke, H.,Emsley, J.
A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain.
Blood, 127:2915-2923, 2016
Cited by
PubMed: 27006387
DOI: 10.1182/blood-2015-10-676122
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.85 Å)
Structure validation

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