5HZI

Crystal structure of photoinhibitable Intersectin1 containing C450M mutant LOV2 domain

Summary for 5HZI

Entry DOI	10.2210/pdb5hzi/pdb
Descriptor	Intersectin-1,NPH1-1,Intersectin-1, FLAVIN MONONUCLEOTIDE (3 entities in total)
Functional Keywords	signaling protein, photoswitch, chimera
Biological source	Homo sapiens (Human) More
Cellular location	Endomembrane system : Q15811
Total number of polymer chains	2
Total formula weight	117531.02
Authors	Tarnawski, M.,Dagliyan, O.,Chu, P.H.,Shirvanyants, D.,Dokholyan, N.V.,Hahn, K.M.,Schlichting, I. (deposition date: 2016-02-02, release date: 2016-12-21, Last modification date: 2024-01-10)
Primary citation	Dagliyan, O.,Tarnawski, M.,Chu, P.H.,Shirvanyants, D.,Schlichting, I.,Dokholyan, N.V.,Hahn, K.M. Engineering extrinsic disorder to control protein activity in living cells. Science, 354:1441-1444, 2016 Cited by PubMed: 27980211 DOI: 10.1126/science.aah3404 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation