5HZ9

human FABP3 in complex with 6-Chloro-2-methyl-4-phenyl-quinoline-3-carboxylic acid

Summary for 5HZ9

• Entry DOI: 10.2210/pdb5hz9/pdb
• Descriptor: Fatty acid-binding protein, heart, SULFATE ION, 6-chloranyl-2-methyl-4-phenyl-quinoline-3-carboxylic acid, ... (5 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding, _phenix
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P05413
• Total number of polymer chains: 8
• Total formula weight: 127791.58

Authors

Ehler, A.,Rudolph, M.G. (deposition date: 2016-02-02, release date: 2016-12-14)

• Primary citation: Kuhne, H.,Obst-Sander, U.,Kuhn, B.,Conte, A.,Ceccarelli, S.M.,Neidhart, W.,Rudolph, M.G.,Ottaviani, G.,Gasser, R.,So, S.S.,Li, S.,Zhang, X.,Gao, L.,Myers, M.; Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.; Bioorg. Med. Chem. Lett., 26:5092-5097, 2016; PubMed: 27658368; DOI: 10.1016/j.bmcl.2016.08.071

Experimental method

X-RAY DIFFRACTION (2.3 Å)