5HVK

Crystal structure of LIMK1 mutant D460N in complex with full-length cofilin-1

Summary for 5HVK

• Entry DOI: 10.2210/pdb5hvk/pdb
• Related: 5HVJ
• Descriptor: LIM domain kinase 1, Cofilin-1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
• Functional Keywords: kinase substrate actin-remodeling, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 110950.09

Authors

Hamill, S.,Boggon, T.J. (deposition date: 2016-01-28, release date: 2016-05-04, Last modification date: 2023-09-27)

• Primary citation: Hamill, S.,Lou, H.J.,Turk, B.E.,Boggon, T.J.; Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.; Mol.Cell, 62:397-408, 2016; PubMed: 27153537; DOI: 10.1016/j.molcel.2016.04.001

Experimental method

X-RAY DIFFRACTION (3.5 Å)