5HTK

Human Heart 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase (PFKFB2)

Summary for 5HTK

• Entry DOI: 10.2210/pdb5htk/pdb
• Related: 5HR5
• Descriptor: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2, CITRATE ANION, ADENOSINE-5'-TRIPHOSPHATE, ... (9 entities in total)
• Functional Keywords: human pfkfb2, transferase, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 120344.94

Authors

Crochet, R.B. (deposition date: 2016-01-27, release date: 2016-11-16, Last modification date: 2023-09-27)

• Primary citation: Crochet, R.B.,Kim, J.D.,Lee, H.,Yim, Y.S.,Kim, S.G.,Neau, D.,Lee, Y.H.; Crystal structure of heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) and the inhibitory influence of citrate on substrate binding.; Proteins, 85:117-124, 2017; PubMed: 27802586; DOI: 10.1002/prot.25204

Experimental method

X-RAY DIFFRACTION (2.01 Å)