5HT6
Crystal structure of the SET domain of the human MLL5 methyltransferase
Summary for 5HT6
Entry DOI | 10.2210/pdb5ht6/pdb |
Descriptor | Histone-lysine N-methyltransferase 2E (2 entities in total) |
Functional Keywords | set domain, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus speckle . Isoform NKp44L: Cytoplasm : Q8IZD2 |
Total number of polymer chains | 2 |
Total formula weight | 32214.98 |
Authors | le Maire, A.,Mas-y-Mas, S.,Dumas, C.,Lebedev, A. (deposition date: 2016-01-26, release date: 2016-11-16) |
Primary citation | Mas-Y-Mas, S.,Barbon, M.,Teyssier, C.,Demene, H.,Carvalho, J.E.,Bird, L.E.,Lebedev, A.,Fattori, J.,Schubert, M.,Dumas, C.,Bourguet, W.,le Maire, A. The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity. Plos One, 11:e0165139-e0165139, 2016 Cited by PubMed: 27812132DOI: 10.1371/journal.pone.0165139 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.093 Å) |
Structure validation
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