5HPY

Crystal Structure of RhoA.GDP.MgF3-in complex with human Myosin 9b RhoGAP domain

Summary for 5HPY

• Entry DOI: 10.2210/pdb5hpy/pdb
• Descriptor: Unconventional myosin-IXb, Transforming protein RhoA, TRIFLUOROMAGNESATE, ... (6 entities in total)
• Functional Keywords: complex, rho gtpases, rhogap, gene regulation-signaling protein complex, gene regulation/signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cell cortex : Q13459; Cell membrane; Lipid-anchor; Cytoplasmic side: P61586
• Total number of polymer chains: 4
• Total formula weight: 94855.84

Authors

Yi, F.S.,Ren, J.Q.,Feng, W. (deposition date: 2016-01-21, release date: 2016-07-13, Last modification date: 2023-11-08)

• Primary citation: Yi, F.,Kong, R.,Ren, J.,Zhu, L.,Lou, J.,Wu, J.Y.,Feng, W.; Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism; J.Mol.Biol., 428:3043-3057, 2016; PubMed: 27363609; DOI: 10.1016/j.jmb.2016.06.014

Experimental method

X-RAY DIFFRACTION (2.4 Å)