5HPE

Phosphatase domain of PP5 bound to a phosphomimetic Cdc37 substrate peptide

Summary for 5HPE

Entry DOI	10.2210/pdb5hpe/pdb
Descriptor	Serine/threonine-protein phosphatase 5,Hsp90 co-chaperone Cdc37, MANGANESE (II) ION, COBALT HEXAMMINE(III), ... (4 entities in total)
Functional Keywords	phosphatase domain, enzyme, substrate, phosphorylation, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	1
Total formula weight	40200.90
Authors	Oberoi, J.,Mariotti, L.,Vaughan, C. (deposition date: 2016-01-20, release date: 2016-07-27, Last modification date: 2024-01-10)
Primary citation	Oberoi, J.,Dunn, D.M.,Woodford, M.R.,Mariotti, L.,Schulman, J.,Bourboulia, D.,Mollapour, M.,Vaughan, C.K. Structural and functional basis of protein phosphatase 5 substrate specificity. Proc.Natl.Acad.Sci.USA, 113:9009-9014, 2016 Cited by PubMed: 27466404 DOI: 10.1073/pnas.1603059113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation