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5HP2

Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA sequence derived from S. cerevisiae BDF2 gene with AU basepair at reaction site

Summary for 5HP2
Entry DOI10.2210/pdb5hp2/pdb
Related5ED1 5ED2 5HP3
DescriptorDouble-stranded RNA-specific editase 1, RNA (5'-R(*UP*UP*CP*CP*CP*CP*AP*CP*AP*UP*UP*(8AZ)P*GP*AP*CP*GP*UP*UP*CP*AP*GP*UP*C)-3'), RNA (5'-R(*GP*AP*CP*UP*GP*AP*AP*CP*GP*AP*CP*UP*AP*AP*UP*GP*UP*GP*GP*GP*GP*AP*A)-3'), ... (6 entities in total)
Functional Keywordsdeaminase, human, hydrolase-rna complex, hydrolase/rna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight106177.49
Authors
Matthews, M.M.,Fisher, A.J.,Beal, P.A. (deposition date: 2016-01-20, release date: 2016-04-13, Last modification date: 2023-09-27)
Primary citationMatthews, M.M.,Thomas, J.M.,Zheng, Y.,Tran, K.,Phelps, K.J.,Scott, A.I.,Havel, J.,Fisher, A.J.,Beal, P.A.
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.
Nat.Struct.Mol.Biol., 23:426-433, 2016
Cited by
PubMed: 27065196
DOI: 10.1038/nsmb.3203
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.983 Å)
Structure validation

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