5HK2

Human sigma-1 receptor bound to 4-IBP

Summary for 5HK2

• Entry DOI: 10.2210/pdb5hk2/pdb
• Descriptor: Sigma non-opioid intracellular receptor 1, N-(1-benzylpiperidin-4-yl)-4-iodobenzamide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: sigma-1 receptor, transmembrane receptor, ligand, trimer, membrane protein
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus inner membrane : Q99720
• Total number of polymer chains: 3
• Total formula weight: 81253.03

Authors

Schmidt, H.R.,Zheng, S.,Gurpinar, E.G.,Koehl, A.,Manglik, A.,Kruse, A.C. (deposition date: 2016-01-13, release date: 2016-04-06, Last modification date: 2023-09-27)

• Primary citation: Schmidt, H.R.,Zheng, S.,Gurpinar, E.,Koehl, A.,Manglik, A.,Kruse, A.C.; Crystal structure of the human sigma 1 receptor.; Nature, 532:527-530, 2016; PubMed: 27042935; DOI: 10.1038/nature17391

Experimental method

X-RAY DIFFRACTION (3.2 Å)