5HIS

Crystal Structure of PQS Response Protein PqsE in Complex with 3-methylthiophene-2-carboxylic acid

Summary for 5HIS

• Entry DOI: 10.2210/pdb5his/pdb
• Descriptor: PqsE, FE (III) ION, 3-methylthiophene-2-carboxylic acid, ... (4 entities in total)
• Functional Keywords: quorum sensing, pqs, pqse, inhibitor, pseudomonas, metal binding protein
• Biological source: Pseudomonas aeruginosa PAO1
• Total number of polymer chains: 1
• Total formula weight: 34799.36

Authors

Witzgall, F.,Blankenfeldt, W. (deposition date: 2016-01-12, release date: 2016-04-27, Last modification date: 2024-01-10)

• Primary citation: Zender, M.,Witzgall, F.,Drees, S.L.,Weidel, E.,Maurer, C.K.,Fetzner, S.,Blankenfeldt, W.,Empting, M.,Hartmann, R.W.; Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.; Acs Chem.Biol., 11:1755-1763, 2016; PubMed: 27082157; DOI: 10.1021/acschembio.6b00156

Experimental method

X-RAY DIFFRACTION (1.77 Å)