5HGJ

Structure of integrin alpha1beta1 and alpha2beta1 I-domains explain differential calcium-mediated ligand recognition

Summary for 5HGJ

• Entry DOI: 10.2210/pdb5hgj/pdb
• Descriptor: Integrin alpha-1, CALCIUM ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: integrin, signaling, rossman, i-domain, cell adhesion
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 43921.21

Authors

Brown, K.L.,Banerjee, S.,Feigley, A.,Abe, H.,Blackwell, T.,Zent, R.,Pozzi, A.,Hudson, B.H. (deposition date: 2016-01-08, release date: 2017-04-12, Last modification date: 2024-03-06)

• Primary citation: Brown, K.L.,Banerjee, S.,Feigley, A.,Abe, H.,Blackwell, T.S.,Pozzi, A.,Hudson, B.G.,Zent, R.; Salt-bridge modulates differential calcium-mediated ligand binding to integrin alpha 1- and alpha 2-I domains.; Sci Rep, 8:2916-2916, 2018; PubMed: 29440721; DOI: 10.1038/s41598-018-21231-1

Experimental method

X-RAY DIFFRACTION (1.399 Å)