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5IJD

The crystal structure of mouse TLR4/MD-2/lipid A complex

Replaces:  5HG6
Summary for 5IJD
Entry DOI10.2210/pdb5ijd/pdb
Related5LJB 5LJC
DescriptorToll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywordsimmune response, protein complex, natural agonist, immune system
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains4
Total formula weight177128.66
Authors
Wang, Y.,Su, L.,Morin, M.D.,Jones, B.T.,Whitby, L.R.,Surakattula, M.,Huang, H.,Shi, H.,Choi, J.H.,Wang, K.,Moresco, E.M.,Berger, M.,Zhan, X.,Zhang, H.,Boger, D.L.,Beutler, B. (deposition date: 2016-03-01, release date: 2016-04-27, Last modification date: 2020-07-29)
Primary citationWang, Y.,Su, L.,Morin, M.D.,Jones, B.T.,Whitby, L.R.,Surakattula, M.M.,Huang, H.,Shi, H.,Choi, J.H.,Wang, K.W.,Moresco, E.M.,Berger, M.,Zhan, X.,Zhang, H.,Boger, D.L.,Beutler, B.
TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113:E884-E893, 2016
Cited by
PubMed: 26831104
DOI: 10.1073/pnas.1525639113
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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