5HF6
Crystal structure of human acetylcholinesterase in complex with paraoxon in the aged state
Summary for 5HF6
| Entry DOI | 10.2210/pdb5hf6/pdb |
| Related | 5HF5 5HF8 5HF9 5HFA |
| Descriptor | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL DIHYDROGEN PHOSPHATE, ... (6 entities in total) |
| Functional Keywords | acetylcholinesterase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 120756.87 |
| Authors | Franklin, M.F.,Rudolph, M.J.,Ginter, C.,Cassidy, M.S.,Cheung, J. (deposition date: 2016-01-06, release date: 2016-06-22, Last modification date: 2023-09-27) |
| Primary citation | Franklin, M.C.,Rudolph, M.J.,Ginter, C.,Cassidy, M.S.,Cheung, J. Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84:1246-1256, 2016 Cited by PubMed: 27191504DOI: 10.1002/prot.25073 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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