5HAU

Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome

This is a non-PDB format compatible entry.

Summary for 5HAU

• Entry DOI: 10.2210/pdb5hau/pdb
• Related: 5HCP 5HCQ 5HCR 5HD1
• Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... (63 entities in total)
• Functional Keywords: bac7, antimicrobial peptide, antibiotic, 70s ribosome, inhibition of translation, peptidyl transferase inhibitors, 50s ribosomal subunit, peptide exit tunnel, ribosome-antibiotic complex, ribosome/antibiotic
• Biological source: Thermus thermophilus; More
• Total number of polymer chains: 116
• Total formula weight: 4713150.01

Authors

Gagnon, M.G.,Roy, R.N.,Lomakin, I.B.,Florin, T.,Mankin, A.S.,Steitz, T.A. (deposition date: 2015-12-30, release date: 2016-04-06, Last modification date: 2024-03-06)

• Primary citation: Gagnon, M.G.,Roy, R.N.,Lomakin, I.B.,Florin, T.,Mankin, A.S.,Steitz, T.A.; Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition.; Nucleic Acids Res., 44:2439-2450, 2016; PubMed: 26809677; DOI: 10.1093/nar/gkw018

Experimental method

X-RAY DIFFRACTION (3 Å)