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5H8B

Crystal structure of CK2 with compound 2

Summary for 5H8B
Entry DOI10.2210/pdb5h8b/pdb
Related5H8E 5H8G
DescriptorCasein kinase II subunit alpha, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordskinase, inhibitor, ck2, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : P68400
Total number of polymer chains2
Total formula weight83060.11
Authors
Ferguson, A.D. (deposition date: 2015-12-23, release date: 2016-02-10, Last modification date: 2023-09-27)
Primary citationDowling, J.E.,Alimzhanov, M.,Bao, L.,Chuaqui, C.,Denz, C.R.,Jenkins, E.,Larsen, N.A.,Lyne, P.D.,Pontz, T.,Ye, Q.,Holdgate, G.A.,Snow, L.,O'Connell, N.,Ferguson, A.D.
Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo.
Acs Med.Chem.Lett., 7:300-305, 2016
Cited by
PubMed: 26985319
DOI: 10.1021/acsmedchemlett.5b00452
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

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