5H7G

Crystal structure of the BCL6 BTB domain in complex with F1324

Summary for 5H7G

• Entry DOI: 10.2210/pdb5h7g/pdb
• Related: 5H7H
• Descriptor: B-cell lymphoma 6 protein, F1324 peptide, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transcription repressor, complex, inhibitor, transcription-inhibitor complex, transcription/inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P41182
• Total number of polymer chains: 4
• Total formula weight: 36217.64

Authors

Sogabe, S.,Ida, K.,Lane, W.,Snell, G. (deposition date: 2016-11-18, release date: 2016-12-07, Last modification date: 2023-11-08)

• Primary citation: Sakamoto, K.,Sogabe, S.,Kamada, Y.,Sakai, N.,Asano, K.,Yoshimatsu, M.,Ida, K.,Imaeda, Y.,Sakamoto, J.I.; Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.; Biochem. Biophys. Res. Commun., 482:310-316, 2017; PubMed: 27856253; DOI: 10.1016/j.bbrc.2016.11.060

Experimental method

X-RAY DIFFRACTION (1.85 Å)