5H13
EED in complex with PRC2 allosteric inhibitor EED396
Summary for 5H13
Entry DOI | 10.2210/pdb5h13/pdb |
Related | 5H14 5H15 5H17 5H19 5H24 5H25 |
Descriptor | Polycomb protein EED, GLYCEROL, PRASEODYMIUM ION, ... (5 entities in total) |
Functional Keywords | eed, prc2, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: O75530 |
Total number of polymer chains | 1 |
Total formula weight | 44096.93 |
Authors | |
Primary citation | Li, L.,Zhang, H.,Zhang, M.,Zhao, M.,Feng, L.,Luo, X.,Gao, Z.,Huang, Y.,Ardayfio, O.,Zhang, J.H.,Lin, Y.,Fan, H.,Mi, Y.,Li, G.,Liu, L.,Feng, L.,Luo, F.,Teng, L.,Qi, W.,Ottl, J.,Lingel, A.,Bussiere, D.E.,Yu, Z.,Atadja, P.,Lu, C.,Li, E.,Gu, J.,Zhao, K. Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12:e0169855-e0169855, 2017 Cited by PubMed: 28072869DOI: 10.1371/journal.pone.0169855 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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