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5H13

EED in complex with PRC2 allosteric inhibitor EED396

Summary for 5H13
Entry DOI10.2210/pdb5h13/pdb
Related5H14 5H15 5H17 5H19 5H24 5H25
DescriptorPolycomb protein EED, GLYCEROL, PRASEODYMIUM ION, ... (5 entities in total)
Functional Keywordseed, prc2, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
Cellular locationNucleus: O75530
Total number of polymer chains1
Total formula weight44096.93
Authors
Zhao, K.,Zhao, M.,Luo, X.,Zhang, H. (deposition date: 2016-10-08, release date: 2017-01-25, Last modification date: 2023-11-08)
Primary citationLi, L.,Zhang, H.,Zhang, M.,Zhao, M.,Feng, L.,Luo, X.,Gao, Z.,Huang, Y.,Ardayfio, O.,Zhang, J.H.,Lin, Y.,Fan, H.,Mi, Y.,Li, G.,Liu, L.,Feng, L.,Luo, F.,Teng, L.,Qi, W.,Ottl, J.,Lingel, A.,Bussiere, D.E.,Yu, Z.,Atadja, P.,Lu, C.,Li, E.,Gu, J.,Zhao, K.
Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12:e0169855-e0169855, 2017
Cited by
PubMed: 28072869
DOI: 10.1371/journal.pone.0169855
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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