5GRH

Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+)

Summary for 5GRH

• Entry DOI: 10.2210/pdb5grh/pdb
• Related: 5GRE 5GRF 5GRI 5GRL
• Descriptor: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, MAGNESIUM ION (3 entities in total)
• Functional Keywords: apo-form, isocitrate dehydrogenase, oxidoreductase
• Biological source: Homo sapiens (Human); More
• Cellular location: Mitochondrion: P50213 P51553
• Total number of polymer chains: 2
• Total formula weight: 75574.00

Authors

Ma, T.,Peng, Y. (deposition date: 2016-08-11, release date: 2017-02-15, Last modification date: 2023-11-08)

• Primary citation: Ma, T.,Peng, Y.,Huang, W.,Ding, J.; Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.; Sci Rep, 7:40921-40921, 2017; PubMed: 28098230; DOI: 10.1038/srep40921

Experimental method

X-RAY DIFFRACTION (2.8 Å)