5GJ4

Structure of NS2B-NS3 Protease from Zika Virus caught after self-cleavage

Summary for 5GJ4

Entry DOI	10.2210/pdb5gj4/pdb
Descriptor	Serine protease subunit NS2B, Serine protease NS3, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	zika virus protease, antiviral drug discovery, hydrolase
Biological source	Zika virus (strain Mr 766) (ZIKV) More
Cellular location	Virion membrane ; Multi-pass membrane protein : A0A142IX72 A0A142IX72
Total number of polymer chains	8
Total formula weight	102878.54
Authors	Phoo, W.W.,Li, Y. (deposition date: 2016-06-27, release date: 2016-10-26, Last modification date: 2023-11-08)
Primary citation	Phoo, W.W.,Li, Y.,Zhang, Z.,Lee, M.Y.,Loh, Y.R.,Tan, Y.B.,Ng, E.Y.,Lescar, J.,Kang, C.,Luo, D. Structure of the NS2B-NS3 protease from Zika virus after self-cleavage. Nat Commun, 7:13410-13410, 2016 Cited by PubMed: 27845325 DOI: 10.1038/ncomms13410 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.839 Å)

Structure validation