5GGI

Crystal structure of human protein O-mannose beta-1,2-N-acetylglucosaminyltransferase in complex with Mn, UDP and Mannosyl-peptide

Summary for 5GGI

Entry DOI	10.2210/pdb5ggi/pdb
Related	5GGF 5GGG 5GGJ 5GGK 5GGL 5GGN 5GGO 5GGP
Descriptor	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1, mannosyl-peptide, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywords	glycosyltransferease, o-mannosylation, alpha-dystroglycan, transferase, sugar binding protein-substrate complex, sugar binding protein/substrate
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	134112.29
Authors	Kuwabara, N.,Senda, T.,Kato, R. (deposition date: 2016-06-16, release date: 2016-08-10, Last modification date: 2024-03-20)
Primary citation	Kuwabara, N.,Manya, H.,Yamada, T.,Tateno, H.,Kanagawa, M.,Kobayashi, K.,Akasaka-Manya, K.,Hirose, Y.,Mizuno, M.,Ikeguchi, M.,Toda, T.,Hirabayashi, J.,Senda, T.,Endo, T.,Kato, R. Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan Proc.Natl.Acad.Sci.USA, 113:9280-9285, 2016 Cited by PubMed: 27493216 DOI: 10.1073/pnas.1525545113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation