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5G0I

Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A

Summary for 5G0I
Entry DOI10.2210/pdb5g0i/pdb
Related5G0F 5G0G 5G0H 5G0J
DescriptorHDAC6, ZINC ION, POTASSIUM ION, ... (7 entities in total)
Functional Keywordscell cycle, histone, histone deacetylase
Biological sourceDANIO RERIO (ZEBRAFISH)
Total number of polymer chains2
Total formula weight180794.70
Authors
Miyake, Y.,Keusch, J.J.,Wang, L.,Saito, M.,Hess, D.,Wang, X.,Melancon, B.J.,Helquist, P.,Gut, H.,Matthias, P. (deposition date: 2016-03-18, release date: 2016-07-27, Last modification date: 2024-01-10)
Primary citationMiyake, Y.,Keusch, J.J.,Wang, L.,Saito, M.,Hess, D.,Wang, X.,Melancon, B.J.,Helquist, P.,Gut, H.,Matthias, P.
Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition
Nat.Chem.Biol., 12:748-, 2016
Cited by
PubMed: 27454931
DOI: 10.1038/NCHEMBIO.2140
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.99 Å)
Structure validation

217705

数据于2024-03-27公开中

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