5G0I
Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A
Summary for 5G0I
Entry DOI | 10.2210/pdb5g0i/pdb |
Related | 5G0F 5G0G 5G0H 5G0J |
Descriptor | HDAC6, ZINC ION, POTASSIUM ION, ... (7 entities in total) |
Functional Keywords | cell cycle, histone, histone deacetylase |
Biological source | DANIO RERIO (ZEBRAFISH) |
Total number of polymer chains | 2 |
Total formula weight | 180794.70 |
Authors | Miyake, Y.,Keusch, J.J.,Wang, L.,Saito, M.,Hess, D.,Wang, X.,Melancon, B.J.,Helquist, P.,Gut, H.,Matthias, P. (deposition date: 2016-03-18, release date: 2016-07-27, Last modification date: 2024-01-10) |
Primary citation | Miyake, Y.,Keusch, J.J.,Wang, L.,Saito, M.,Hess, D.,Wang, X.,Melancon, B.J.,Helquist, P.,Gut, H.,Matthias, P. Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition Nat.Chem.Biol., 12:748-, 2016 Cited by PubMed: 27454931DOI: 10.1038/NCHEMBIO.2140 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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