5FV9

Crystal structure of GalNAc-T2 in complex with compound 16d

Summary for 5FV9

Entry DOI	10.2210/pdb5fv9/pdb
Descriptor	GALNAC-T2, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... (7 entities in total)
Functional Keywords	transferase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein : Q10471
Total number of polymer chains	6
Total formula weight	394569.44
Authors	Ghirardello, M.,Rivas, M.,Lacetera, A.,Delso, I.,Lira-Navarrete, E.,Tejero, T.,Martin-Santamaria, S.,Hurtado-Guerrero, R.,Merino, P. (deposition date: 2016-02-03, release date: 2016-03-09, Last modification date: 2024-01-10)
Primary citation	Ghirardello, M.,De Las Rivas, M.,Lacetera, A.,Delso, I.,Lira-Navarrete, E.,Tejero, T.,Martin-Santamaria, S.,Hurtado-Guerrero, R.,Merino, P. Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less-Polar Conjugates. Chemistry, 22:7215-, 2016 Cited by PubMed: 27071848 DOI: 10.1002/CHEM.201600467 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.07 Å)

Structure validation