5FQL

Insights into Hunter syndrome from the structure of iduronate-2- sulfatase

Summary for 5FQL

Entry DOI	10.2210/pdb5fql/pdb
Descriptor	IDURONATE-2-SULFATASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywords	hydrolase, hunter syndrome
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	62584.76
Authors	Demydchuk, M.,Hill, C.H.,Zhou, A.,Bunkoczi, G.,Stein, P.E.,Marchesan, D.,Deane, J.E.,Read, R.J. (deposition date: 2015-12-11, release date: 2017-01-18, Last modification date: 2020-07-29)
Primary citation	Demydchuk, M.,Hill, C.H.,Zhou, A.,Bunkoczi, G.,Stein, P.E.,Marchesan, D.,Deane, J.E.,Read, R.J. Insights into Hunter syndrome from the structure of iduronate-2-sulfatase. Nat Commun, 8:15786-15786, 2017 Cited by PubMed: 28593992 DOI: 10.1038/ncomms15786 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation