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5FN5

Cryo-EM structure of gamma secretase in class 3 of the apo- state ensemble

Summary for 5FN5
Entry DOI10.2210/pdb5fn5/pdb
Related5FN2 5FN3 5FN4
EMDB information3240
DescriptorNicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... (4 entities in total)
Functional Keywordshydrolase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight172253.08
Authors
Bai, X.C.,Rajendra, E.,Yang, G.H.,Shi, Y.G.,Scheres, S.H.W. (deposition date: 2015-11-10, release date: 2015-12-16, Last modification date: 2019-09-11)
Primary citationBai, X.C.,Rajendra, E.,Yang, G.,Shi, Y.,Scheres, S.H.
Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4:-, 2015
Cited by
PubMed: 26623517
DOI: 10.7554/eLife.11182
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.3 Å)
Structure validation

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