5FN4

Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble

Summary for 5FN4

• Entry DOI: 10.2210/pdb5fn4/pdb
• Related: 5FN2 5FN3 5FN5
• EMDB information: 3239
• Descriptor: Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 174048.04

Authors

Bai, X.C.,Rajendra, E.,Yang, G.H.,Shi, Y.G.,Scheres, S.H.W. (deposition date: 2015-11-10, release date: 2015-12-16, Last modification date: 2019-09-11)

• Primary citation: Bai, X.C.,Rajendra, E.,Yang, G.,Shi, Y.,Scheres, S.H.; Sampling the conformational space of the catalytic subunit of human gamma-secretase.; Elife, 4:-, 2015; PubMed: 26623517; DOI: 10.7554/eLife.11182

Experimental method

ELECTRON MICROSCOPY (4 Å)