5FG5

Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe

Summary for 5FG5

• Entry DOI: 10.2210/pdb5fg5/pdb
• Descriptor: Peregrin, ~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide, NITRATE ION, ... (4 entities in total)
• Functional Keywords: peregrin, moz-morf complex, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P55201
• Total number of polymer chains: 2
• Total formula weight: 28230.28

Authors

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Brennan, P.E.,Knapp, S. (deposition date: 2015-12-20, release date: 2015-12-30, Last modification date: 2024-01-10)

• Primary citation: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Savitsky, P.,Chaikuad, A.,Fedorov, O.,Nunez-Alonso, G.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Brennan, P.E.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)