5FFY

Crystal structure of the bromodomain of human BRPF1 in complex with a benzimidazole ligand

Summary for 5FFY

• Entry DOI: 10.2210/pdb5ffy/pdb
• Descriptor: Peregrin, 4-ethyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)benzenesulfonamide (3 entities in total)
• Functional Keywords: peregrin, moz-morf complex, transcription
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P55201
• Total number of polymer chains: 1
• Total formula weight: 14079.14

Authors

Tallant, C.,Savitsky, P.,Nunez-Alonso, G.,Kopec, J.,Fedorov, O.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S. (deposition date: 2015-12-19, release date: 2015-12-30, Last modification date: 2024-01-10)

• Primary citation: Tallant, C.,Savitsky, P.,Nunez-Alonso, G.,Kopec, J.,Fedorov, O.,Filippakopoulos, P.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.; Crystal structure of the bromodomain of human BRPF1 in complex with a benzimidazole ligand; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)