5F3J
Crystal structure of DBP in complex with inhibitory monoclonal antibody 2D10
Summary for 5F3J
| Entry DOI | 10.2210/pdb5f3j/pdb |
| Descriptor | Duffy receptor, Antibody 2D10 single chain variable fragment (2 entities in total) |
| Functional Keywords | plasmodium, vivax, duffy binding protein, dbp, antibody, malaria, scfv, neutralizing, interaction, immune, blocking, invasion, vaccine, therapeutic, immune system |
| Biological source | Plasmodium vivax (strain Salvador I) More |
| Total number of polymer chains | 4 |
| Total formula weight | 139676.00 |
| Authors | Chen, E.,Salinas, N.D.,Tolia, N.H. (deposition date: 2015-12-02, release date: 2016-05-18, Last modification date: 2023-09-27) |
| Primary citation | Chen, E.,Salinas, N.D.,Huang, Y.,Ntumngia, F.,Plasencia, M.D.,Gross, M.L.,Adams, J.H.,Tolia, N.H. Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein. Proc.Natl.Acad.Sci.USA, 113:6277-6282, 2016 Cited by PubMed: 27194724DOI: 10.1073/pnas.1600488113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.001 Å) |
Structure validation
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