5F0P

Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled)

Summary for 5F0P

Entry DOI	10.2210/pdb5f0p/pdb
Related	2FAU 2R17 5F0J 5F0K 5F0L 5F0M
Descriptor	Vacuolar protein sorting-associated protein 35, Vacuolar protein sorting-associated protein 26A, Sorting nexin-3, ... (9 entities in total)
Functional Keywords	protein transport, retromer, sorting nexin
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: Q96QK1 O75436 Early endosome : O60493 Isoform 2: Cell membrane ; Multi- pass membrane protein . Endosome membrane ; Multi-pass membrane protein : P49281
Total number of polymer chains	4
Total formula weight	114930.16
Authors	Lucas, M.,Gershlick, D.,Vidaurrazaga, A.,Rojas, A.L.,Bonifacino, J.S.,Hierro, A. (deposition date: 2015-11-27, release date: 2016-12-07, Last modification date: 2024-01-10)
Primary citation	Lucas, M.,Gershlick, D.C.,Vidaurrazaga, A.,Rojas, A.L.,Bonifacino, J.S.,Hierro, A. Structural Mechanism for Cargo Recognition by the Retromer Complex. Cell, 167:1623-1635.e14, 2016 Cited by PubMed: 27889239 DOI: 10.1016/j.cell.2016.10.056 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation