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5EZY

Crystal structure of T2R-TTL-taccalonolide AJ complex

Summary for 5EZY
Entry DOI10.2210/pdb5ezy/pdb
DescriptorTubulin alpha-1B chain, taccalonolide AJ, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
Functional Keywordstubulin, complex, inhibitor, structural protein
Biological sourceRattus norvegicus (Rat)
More
Cellular locationCytoplasm, cytoskeleton: Q2XVP4 Q6B856
Golgi apparatus : P63043
Total number of polymer chains6
Total formula weight265748.22
Authors
Wang, Y.,Yu, Y.,Chen, Q.,Yang, J. (deposition date: 2015-11-27, release date: 2017-01-11, Last modification date: 2023-11-08)
Primary citationWang, Y.,Yu, Y.,Li, G.B.,Li, S.A.,Wu, C.,Gigant, B.,Qin, W.,Chen, H.,Wu, Y.,Chen, Q.,Yang, J.
Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8:15787-15787, 2017
Cited by
PubMed: 28585532
DOI: 10.1038/ncomms15787
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

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