5EZI

Crystal Structure of Fab of parasite invasion inhibitory antibody c1 - hexagonal form

Summary for 5EZI

Entry DOI	10.2210/pdb5ezi/pdb
Descriptor	Fab c12 heavy chain, Fab c12 Light chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	malaria inhibitory antibody, fab, immune system, cyrpa
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	49021.70
Authors	Favuzza, P.,Pluschke, G.,Rudolph, M.G. (deposition date: 2015-11-26, release date: 2017-01-25, Last modification date: 2020-07-29)
Primary citation	Favuzza, P.,Guffart, E.,Tamborrini, M.,Scherer, B.,Dreyer, A.M.,Rufer, A.C.,Erny, J.,Hoernschemeyer, J.,Thoma, R.,Schmid, G.,Gsell, B.,Lamelas, A.,Benz, J.,Joseph, C.,Matile, H.,Pluschke, G.,Rudolph, M.G. Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody. Elife, 6:-, 2017 Cited by PubMed: 28195038 DOI: 10.7554/eLife.20383 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.61 Å)

Structure validation