5ETF

Structure of dead kinase MAPK14 with bound the KIM domain of MKK6

Summary for 5ETF

• Entry DOI: 10.2210/pdb5etf/pdb
• Descriptor: Mitogen-activated protein kinase 14, Dual specificity mitogen-activated protein kinase kinase 6 (3 entities in total)
• Functional Keywords: mapk14, mkk6, kim domain, peptide-protein complex, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : Q16539; Nucleus : P52564
• Total number of polymer chains: 2
• Total formula weight: 42999.23

Authors

Pellegrini, E.,Palencia, A.,Braun, L.,Kapp, U.,Bougdour, A.,Belrhali, H.,Bowler, M.W.,Hakimi, M. (deposition date: 2015-11-17, release date: 2016-10-26, Last modification date: 2017-01-18)

• Primary citation: Pellegrini, E.,Palencia, A.,Braun, L.,Kapp, U.,Bougdour, A.,Belrhali, H.,Bowler, M.W.,Hakimi, M.A.; Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist.; Structure, 25:16-26, 2017; PubMed: 27889209; DOI: 10.1016/j.str.2016.10.011

Experimental method

X-RAY DIFFRACTION (2.4 Å)