5ETC

Structure of inactive MAPK14 with ordered Activation Loop

Summary for 5ETC

Entry DOI	10.2210/pdb5etc/pdb
Descriptor	Mitogen-activated protein kinase 14, SULFATE ION (3 entities in total)
Functional Keywords	mapk14, inactive kinase, activation loop, mapk, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: Q16539
Total number of polymer chains	1
Total formula weight	41812.73
Authors	Kapp, U.,Pellegrini, E.,Bowler, M.W. (deposition date: 2015-11-17, release date: 2016-01-20, Last modification date: 2023-09-27)
Primary citation	Juyoux, P.,Galdadas, I.,Gobbo, D.,von Velsen, J.,Pelosse, M.,Tully, M.,Vadas, O.,Gervasio, F.L.,Pellegrini, E.,Bowler, M.W. Architecture of the MKK6-p38 alpha complex defines the basis of MAPK specificity and activation. Science, 381:1217-1225, 2023 Cited by PubMed: 37708276 DOI: 10.1126/science.add7859 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.422 Å)

Structure validation