5EQ3

Crystal structure of the SrpA adhesin from Streptococcus sanguinis with a sialyl galactose disaccharide bound

Summary for 5EQ3

• Entry DOI: 10.2210/pdb5eq3/pdb
• Related: 5EQ2 5EQ3
• Descriptor: Platelet-binding glycoprotein, N-glycolyl-alpha-neuraminic acid-(2-3)-methyl beta-D-galactopyranoside, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: bacterial adhesin, lectin, immunoglobulin fold, serine-rich repeat, sugar binding protein
• Biological source: Streptococcus sanguinis
• Total number of polymer chains: 2
• Total formula weight: 45072.77

Authors

Loukachevitch, L.V.,McCulloch, K.M.,Vann, K.R.,Wawrzak, Z.,Anderson, S.,Iverson, T.M. (deposition date: 2015-11-12, release date: 2016-01-27, Last modification date: 2024-03-06)

• Primary citation: Bensing, B.A.,Loukachevitch, L.V.,McCulloch, K.M.,Yu, H.,Vann, K.R.,Wawrzak, Z.,Anderson, S.,Chen, X.,Sullam, P.M.,Iverson, T.M.; Structural Basis for Sialoglycan Binding by the Streptococcus sanguinis SrpA Adhesin.; J.Biol.Chem., 291:7230-7240, 2016; PubMed: 26833566; DOI: 10.1074/jbc.M115.701425

Experimental method

X-RAY DIFFRACTION (2 Å)