5EPP

Structural Insights into the Interaction of p97 N-terminus Domain and VBM Motif in Rhomboid Protease, RHBDL4

Summary for 5EPP

Entry DOI	10.2210/pdb5epp/pdb
Descriptor	Transitional endoplasmic reticulum ATPase, Rhomboid-related protein 4 (3 entities in total)
Functional Keywords	beta-barrel, atpase, rhbdl4 vbm motif, ubiquitin, hydrolase
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm, cytosol: P55072 Membrane ; Multi-pass membrane protein : Q8TEB9
Total number of polymer chains	2
Total formula weight	22809.14
Authors	Lim, J.J.,Lee, Y.,Ly, T.T.,Kang, J.Y.,Lee, J.-G.,An, J.Y.,Youn, H.-S.,Park, K.R.,Kim, T.G.,Yang, J.K.,Jun, Y.,Eom, S.H. (deposition date: 2015-11-12, release date: 2016-09-14, Last modification date: 2023-11-08)
Primary citation	Lim, J.J.,Lee, Y.,Ly, T.T.,Kang, J.Y.,Lee, J.G.,An, J.Y.,Youn, H.S.,Park, K.R.,Kim, T.G.,Yang, J.K.,Jun, Y.,Eom, S.H. Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4. Biochem.J., 473:2863-2880, 2016 Cited by PubMed: 27407164 DOI: 10.1042/BCJ20160237 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation