5ENZ

S. aureus MnaA-UDP co-structure

Summary for 5ENZ

• Entry DOI: 10.2210/pdb5enz/pdb
• Descriptor: UDP-GlcNAc 2-epimerase, URIDINE-5'-DIPHOSPHATE, SULFATE ION, ... (6 entities in total)
• Functional Keywords: sugar-nucleotide epimerase, rossmann fold, two domains, glycogen phosphorylase superfamily, udp, dimer, isomerase
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 2
• Total formula weight: 89008.87

Authors

Fischmann, T.O. (deposition date: 2015-11-09, release date: 2016-04-27, Last modification date: 2023-09-27)

• Primary citation: Mann, P.A.,Muller, A.,Wolff, K.A.,Fischmann, T.,Wang, H.,Reed, P.,Hou, Y.,Li, W.,Muller, C.E.,Xiao, J.,Murgolo, N.,Sher, X.,Mayhood, T.,Sheth, P.R.,Mirza, A.,Labroli, M.,Xiao, L.,McCoy, M.,Gill, C.J.,Pinho, M.G.,Schneider, T.,Roemer, T.; Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets.; Plos Pathog., 12:e1005585-e1005585, 2016; PubMed: 27144276; DOI: 10.1371/journal.ppat.1005585

Experimental method

X-RAY DIFFRACTION (1.91 Å)