5EKG

Crystallization and X-ray Diffraction Data Collection of Importin-alpha from Mus musculus Complexed with a XPG NLS Peptide, fragment 2

Summary for 5EKG

• Entry DOI: 10.2210/pdb5ekg/pdb
• Related: 5EKF
• Descriptor: XPG2 peptide, Importin subunit alpha-1 (2 entities in total)
• Functional Keywords: importin alpha, nuclear import pathway, nuclear localization sequence (nls), dna repair proteins, nucleotide excision repair, xpg protein, protein binding
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cytoplasm : P52293
• Total number of polymer chains: 3
• Total formula weight: 60150.60

Authors

Barros, A.C.,Takeda, A.A.S.,Fontes, M.R.M. (deposition date: 2015-11-03, release date: 2016-02-10, Last modification date: 2024-03-06)

• Primary citation: Barros, A.C.,Takeda, A.A.,Dreyer, T.R.,Velazquez-Campoy, A.,Kobe, B.,Fontes, M.R.; Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence.; J.Mol.Biol., 428:2120-2131, 2016; PubMed: 26812207; DOI: 10.1016/j.jmb.2016.01.019

Experimental method

X-RAY DIFFRACTION (2.8 Å)