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5EIH

mAChE-TZ2/PA5 complex

Summary for 5EIH
Entry DOI10.2210/pdb5eih/pdb
Related5EIE
DescriptorAcetylcholinesterase, ~{N}-(2-azidoethyl)-1,2,3,4-tetrahydroacridin-9-amine, 5-hept-6-ynyl-6-phenyl-phenanthridin-5-ium-3,8-diamine, ... (6 entities in total)
Functional Keywordsacetylcholinesterase, inhibitor, click chemistry, peripheral anionic site, hydrolase
Biological sourceMus musculus (Mouse)
Cellular locationCell junction, synapse. Isoform H: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side: P21836
Total number of polymer chains2
Total formula weight120844.56
Authors
Bourne, Y.,Marchot, P. (deposition date: 2015-10-29, release date: 2016-01-20, Last modification date: 2024-01-10)
Primary citationBourne, Y.,Sharpless, K.B.,Taylor, P.,Marchot, P.
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase.
J.Am.Chem.Soc., 138:1611-1621, 2016
Cited by
PubMed: 26731630
DOI: 10.1021/jacs.5b11384
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

217705

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