5EIB

Crystal structure of CPAP PN2-3 C-terminal loop-helix in complex with DARPin-tubulin

Summary for 5EIB

Entry DOI	10.2210/pdb5eib/pdb
Descriptor	Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed ankyrin repeat protein, ... (7 entities in total)
Functional Keywords	pn2-3, tubulin complex, cell cycle
Biological source	synthetic construct More
Cellular location	Cytoplasm, cytoskeleton: P81947 Q6B856 Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : Q9HC77
Total number of polymer chains	4
Total formula weight	121968.73
Authors	Li, H.,Zheng, X. (deposition date: 2015-10-29, release date: 2016-10-26, Last modification date: 2023-11-08)
Primary citation	Zheng, X.,Ramani, A.,Soni, K.,Gottardo, M.,Zheng, S.,Ming Gooi, L.,Li, W.,Feng, S.,Mariappan, A.,Wason, A.,Widlund, P.,Pozniakovsky, A.,Poser, I.,Deng, H.,Ou, G.,Riparbelli, M.,Giuliano, C.,Hyman, A.A.,Sattler, M.,Gopalakrishnan, J.,Li, H. Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length Nat Commun, 7:11874-11874, 2016 Cited by PubMed: 27306797 DOI: 10.1038/ncomms11874 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation