5EDC

human FABP4 in complex with 6-Chloro-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid at 1.29A

Summary for 5EDC

Entry DOI	10.2210/pdb5edc/pdb
Descriptor	Fatty acid-binding protein, adipocyte, 6-chloranyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid, SULFATE ION, ... (4 entities in total)
Functional Keywords	lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P15090
Total number of polymer chains	1
Total formula weight	15466.01
Authors	Rudolph, M.G.,Ehler, A. (deposition date: 2015-10-21, release date: 2016-03-09, Last modification date: 2016-05-25)
Primary citation	Kuhn, B.,Guba, W.,Hert, J.,Banner, D.,Bissantz, C.,Ceccarelli, S.,Haap, W.,Korner, M.,Kuglstatter, A.,Lerner, C.,Mattei, P.,Neidhart, W.,Pinard, E.,Rudolph, M.G.,Schulz-Gasch, T.,Woltering, T.,Stahl, M. A Real-World Perspective on Molecular Design. J.Med.Chem., 59:4087-4102, 2016 Cited by PubMed: 26878596 DOI: 10.1021/acs.jmedchem.5b01875 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.29 Å)

Structure validation