5EAT

5-EPI-ARISTOLOCHENE SYNTHASE FROM NICOTIANA TABACUM WITH SUBSTRATE ANALOG FARNESYL HYDROXYPHOSPHONATE

Summary for 5EAT

Entry DOI	10.2210/pdb5eat/pdb
Descriptor	5-EPI-ARISTOLOCHENE SYNTHASE, MAGNESIUM ION, 1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE PHOSPHONIC ACID, ... (4 entities in total)
Functional Keywords	isoprenoid synthase, isoprenoid cyclase, 5-epi-aristolochene synthase, isoprenoid biosynthesis, natural products biosynthesis
Biological source	Nicotiana tabacum (common tobacco)
Cellular location	Cytoplasm: Q40577
Total number of polymer chains	1
Total formula weight	63442.68
Authors	Starks, C.M.,Back, K.,Chappell, J.,Noel, J.P. (deposition date: 1997-07-24, release date: 1997-11-12, Last modification date: 2023-08-09)
Primary citation	Starks, C.M.,Back, K.,Chappell, J.,Noel, J.P. Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. Science, 277:1815-1820, 1997 Cited by PubMed: 9295271 DOI: 10.1126/science.277.5333.1815 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation